Metabolic Wellness Profile Review








Metabolic Wellness Profile: Summary

In this Lab&Learn, Dr. Aron Gonshor joins to discuss metabolic wellness through the lens of the Metabolic Wellness Profile, a test done using dried urine samples. The discussion covers three main aspects: protein metabolism, liver detoxification, and oxidative stress. 

Dr. Gonshor provides an in-depth look at protein digestion, particularly focusing on the implications of indican levels which signal issues like dysbiosis and protein malabsorption, and various solutions including enzyme supplementation and dietary adjustments. The podcast also delves into liver detoxification, emphasizing the liver’s numerous functions and the problems arising from dysfunction, such as oxidative stress and chronic illnesses. Key points include the importance of bile acids and their role in detoxification, and the impacts of external and internal toxins on liver health. 

Finally, oxidative stress is explained as a contributor to cellular damage and chronic conditions, with an emphasis on the significance of the 8-OHdG biomarker for evaluating cumulative cellular oxidative stress, and how lifestyle and dietary adjustments can help mitigate these effects. 

The episode concludes with a Q&A session addressing various related topics, including the significance of detecting these biomarkers and potential next steps for affected individuals.

Metabolic Wellness Profile: Topics

00:00 Introduction to Dr. Aron Gonshor

00:29 Overview of Metabolic Wellness Profile

03:54 Understanding Protein Metabolism

09:16 Liver Detoxification Explained

23:59 Oxidative Stress and Its Impact

27:48 Understanding Chronic Inflammation and Oxidative Stress

28:58 Key Biomarker: 8-OHdG

30:07 Sources and Effects of Oxidative Stress

33:41 Healthy Lifestyle Choices and Antioxidant Supplements

34:58 Melatonin: More Than Just Sleep

36:44 Reading and Interpreting Lab Reports

37:45 Addressing High Indican Levels

39:40 Elevated 8-OHdG and Its Implications

42:36 Low Bile Acids: Causes and Action Plan

44:15 Q&A Session

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